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Lexapro as a Depression Treatment

Effective Control of Symptoms — With Fewer Side Effects

Lexapro has been proven to be an effective treatment for depression. In controlled studies, Lexapro significantly improved the symptoms of depression for many patients beginning at week 1 or 2 (full antidepressant effect may take 4 to 6 weeks).

In clinical trials, the number of people who stopped taking their medicine due to side effects was about the same for people taking Lexapro at 10 mg per day as it was for placebo (sugar pill).

A recent controlled studyA study in which a test treatment is compared with a treatment that has known effects. The control group may receive no treatment, standard treatment (which may be another medicine or another approach to care), or placebo (sugar pill.) of major depressive disorder (MDD)This is a physician's term for a specific type of depression. A person who suffers from a major depressive disorder must have either a depressed mood or a loss of interest or pleasure in daily activities. The person must have these symptoms consistently for at least a two-week period. Furthermore, this mood must represent a change from the person's normal mood. It should also be having a negative impact on his or her daily function, such as family, work, socializing, etc. A depressed mood caused by drugs or alcohol, or one caused by a medical condition, is not considered a major depressive disorder. Remember, only a doctor can properly diagnose this or any other disorder. compared 20 mg/day of Lexapro with 225 mg/day of Effexor XR® (venlafaxine HCl). In this study, Lexapro was found to be just as effective as Effexor. Lexapro was also less likely to cause side effects than Effexor.

Can be used safely in patients who've previously used other depression medicines. Medicines can sometimes work differently in different people. That's why it is not unusual for doctors to recommend that their patients change medicines to get better relief of their symptoms. In one study of patients with depression, patients who started on one medicine but did not respond to it were switched to Lexapro. The other medicines were Celexa, Paxil, Prozac, and Zoloft.

In this study, patients were able to be quickly and safely switched to Lexapro. As many as 69% of the patients who switched to Lexapro responded to treatment, and as many as 56% of them experienced remission. It is important to note that these same response and remission rates may have occurred over time if patients had stayed with their original therapy or switched to a different antidepressant medicine.

Remember, it is important to take your medicine for as long as your healthcare professional advises, even if you start feeling better. Otherwise your symptoms could return or worsen. Full recovery takes time.

Effexor XR is a registered trademark of Wyeth Pharmaceuticals Inc.
Zoloft is a registered trademark of Pfizer Inc.
Paxil is a registered trademark of GlaxoSmithKline.
Prozac is a registered trademark of Eli Lilly and Company.